Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11450008 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL12062810 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL9877797 | 0.68 | ALDH1A1 (0.36) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL1027879 | 0.67 | ALDH1A1 (0.58) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL9877311 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL180055 | 0.65 | ALDH1A1 (0.67) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL1115832 | 0.64 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL9877223 | 0.64 | ALDH1A1 (0.44) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL103850 | 0.64 | ALDH1A1 (1.00) | ALDH1A1TP53TSHRMAPK1HIF1A | |
| SCHEMBL2759656 | 0.63 | ALDH1A1 (0.47) | ALDH1A1TP53TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |