Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23312224 | 0.74 | AOC1 (0.44) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL26575221 | 0.74 | KDM1A (0.43) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL2962223 | 0.70 | TDP1 (0.57) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL27741403 | 0.69 | TDP1 (0.43) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL18893301 | 0.68 | TDP1 (0.41) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL11355172 | 0.67 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL23956092 | 0.65 | IDO1 (0.32) | TDP1IDO1 | |
| SCHEMBL22430546 | 0.64 | TDP1 (0.38) | TDP1IDO1ALDH1A1KDM4ELMNA | |
| SCHEMBL9877797 | 0.64 | ALDH1A1 (0.36) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11467473 | 0.64 | MEN1 (0.39) | TDP1IDO1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |