Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877333 | 0.87 | HPGD (0.44) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9878117 | 0.87 | HPGD (0.42) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9878390 | 0.85 | HPGD (0.40) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9878734 | 0.81 | HPGD (0.53) | HPGDCYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL9567022 | 0.80 | TSHR (0.35) | HPGDCYP1A2POLBALDH1A1L3MBTL1 | |
| SCHEMBL9350427 | 0.80 | NOTUM (0.40) | HPGDCYP1A2POLBALDH1A1L3MBTL1 | |
| SCHEMBL9878923 | 0.80 | POLB (0.43) | HPGDPOLBRAB9ANPC1APEX1 | |
| SCHEMBL9423183 | 0.79 | ALDH1A1 (0.36) | HPGDCYP1A2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL22745804 | 0.79 | MAPT (0.36) | HPGDCYP1A2CYP2C19ALDH1A1GAA | |
| SCHEMBL19827391 | 0.78 | SCN9A (0.39) | POLBCYP2C19APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | claimed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | claimed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | claimed |