Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559779 | 0.83 | RAB9A (0.56) | RAB9AHTTIDO1MAPTNPSR1 | |
| SCHEMBL9877810 | 0.76 | CYP19A1 (0.49) | RAB9AHTTMAPT | |
| SCHEMBL9877393 | 0.74 | RAB9A (0.49) | RAB9AHTTIDO1MAPTNPSR1 | |
| SCHEMBL11520952 | 0.73 | RAB9A (0.48) | RAB9AHTTIDO1MAPTNPSR1 | |
| SCHEMBL11520946 | 0.72 | RAB9A (0.44) | RAB9AHTTIDO1MAPTNPSR1 | |
| SCHEMBL9670638 | 0.72 | IDO1 (0.56) | RAB9AHTTIDO1MAOBHTR2A | |
| SCHEMBL10885468 | 0.72 | RAB9A (0.59) | RAB9AHTTIDO1MAPTNPSR1 | |
| SCHEMBL27847543 | 0.72 | SLC7A5 (0.45) | IDO1MAPTNPSR1ITGA4ITGB7 | |
| SCHEMBL7737719 | 0.72 | RAB9A (0.55) | RAB9AIDO1NPC1ITGA4ITGB7 | |
| SCHEMBL11144069 | 0.71 | RAB9A (0.52) | RAB9AHTTIDO1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |