Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520952 | 0.89 | RAB9A (0.48) | RAB9AHTTMAOAMAOBALDH1A1 | |
| SCHEMBL10885461 | 0.88 | RAB9A (0.54) | RAB9AHTTHTR2AITGA4ITGB7 | |
| SCHEMBL11525587 | 0.81 | ALDH1A1 (0.52) | RAB9AHTTALDH1A1HTR2AIDO1 | |
| SCHEMBL9350698 | 0.77 | RAB9A (0.56) | RAB9AHTTHTR2AITGA4ITGB7 | |
| SCHEMBL11097959 | 0.77 | RAB9A (0.55) | RAB9AHTTHTR2AMAPTIDO1 | |
| SCHEMBL10885468 | 0.76 | RAB9A (0.59) | RAB9AHTTALDH1A1HTR2AITGA4 | |
| SCHEMBL10493299 | 0.75 | RAB9A (0.54) | RAB9AHTTHTR2AITGA4ITGB7 | |
| SCHEMBL8141752 | 0.75 | HTT (0.68) | RAB9AHTTMAOAMAOBALDH1A1 | |
| SCHEMBL1012 | 0.73 | IDO1 (0.58) | RAB9AHTTMAOAMAOBALDH1A1 | |
| SCHEMBL9877808 | 0.72 | RAB9A (0.46) | RAB9AHTTMAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |