Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877922 | 0.92 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL29597632 | 0.92 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL10351576 | 0.91 | KAT2B (0.54) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9515101 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9878203 | 0.89 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL10897993 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9877665 | 0.85 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL9878288 | 0.84 | MAPT (0.61) | ALDH1A1SMN1; SMN2KMT2ATSHRPKM | |
| SCHEMBL10622750 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2ATSHRPKM | |
| SCHEMBL10359926 | 0.81 | POLB (0.46) | ALDH1A1SMN1; SMN2KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0245603-B1 | AROMATIC AMINOSULFONE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0245603-A2 | Aromatic aminosulfone compounds and process for their preparation | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| US-4577015-A | Triphendioxazine vinyl sulphone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| EP-0153599-A2 | Triphenedioxazine vinylsulfonyl dyestuffs | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |