Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597632 | 1.00 | KMT2A (0.58) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL9877899 | 0.92 | ALDH1A1 (0.62) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL9878203 | 0.91 | ALDH1A1 (0.50) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL10351576 | 0.89 | KAT2B (0.54) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL9877665 | 0.88 | KMT2A (0.58) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL9515101 | 0.87 | SMN1; SMN2 (0.53) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL9878288 | 0.87 | MAPT (0.61) | KMT2ATSHRPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL10851653 | 0.86 | KMT2A (0.60) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL10423145 | 0.85 | SLC25A1 (0.47) | KMT2ATSHRTDP1PKMALDH1A1 | |
| SCHEMBL10536600 | 0.85 | KMT2A (0.59) | KMT2ATSHRTDP1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0245603-B1 | AROMATIC AMINOSULFONE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4851527-A | Water-soluble triphendioxazine compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| US-4785098-A | BLUE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0245603-A2 | Aromatic aminosulfone compounds and process for their preparation | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| US-4577015-A | Triphendioxazine vinyl sulphone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| EP-0153599-A2 | Triphenedioxazine vinylsulfonyl dyestuffs | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |