Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877922 | 0.87 | KMT2A (0.58) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL29597632 | 0.87 | KMT2A (0.58) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL9877899 | 0.84 | ALDH1A1 (0.62) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL9878203 | 0.83 | ALDH1A1 (0.50) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL10622787 | 0.83 | ALDH1A1 (0.61) | MAPTKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL10351576 | 0.81 | KAT2B (0.54) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL9877842 | 0.81 | L3MBTL1 (0.46) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL10356896 | 0.81 | KMT2A (0.51) | MAPTPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL10622750 | 0.81 | ALDH1A1 (0.54) | MAPTPOLBPKMKMT2AALDH1A1 | |
| SCHEMBL9878286 | 0.81 | MAPT (0.60) | MAPTPOLBPKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4785098-A | BLUE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0171611-B1 | SUBSTITUTED PHENYLOXETHYL SULPHONES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0171611-A1 | Substituted phenyloxethyl sulphones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-19 | — | — | EP | disclosed |