Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877648 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL9878091 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL11096738 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL10528004 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL6204706 | 0.83 | NPC1 (0.46) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL11122644 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL9877329 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL11094696 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL11094694 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EPKMRAB9A | |
| SCHEMBL6202785 | 0.82 | NPC1 (0.46) | ALDH1A1LMNAKDM4EPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036074-A | In agriculture and horticulture | CIBA-GEIGY CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0385267-A2 | Pyridine derivatives, their preparation and their use as fungicides | CIBA-GEIGY AG (CH) | 1990-09-05 | — | — | EP | disclosed |
| EP-0137456-B1 | DERIVATIVES OF PYRIDINE, PYRAZINE AND PYRIMIDINE AND THEIR USE AS FUNGICIDAL AGENTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-02-10 | — | — | EP | disclosed |
| US-4699652-A | Fungicidal pyridine derivatives for use in agriculture | HOFFMANN-LA ROCHE INC. (US) | 1987-10-13 | — | — | US | disclosed |
| US-4678790-A | AGRICULTURE HORTICULTURE | HOFFMAN-LA ROCHE INC. (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0209854-A2 | Pyridine derivatives and their use as fungicidal agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-01-28 | — | — | EP | disclosed |
| EP-0137456-A1 | Derivatives of pyridine, pyrazine and pyrimidine and their use as fungicidal agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-04-17 | — | — | EP | disclosed |