Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046883 | 0.84 | LMNA (0.54) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9710536 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL27803277 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL4435225 | 0.78 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL24475548 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL2441292 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL28800245 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL521069 | 0.77 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL11445319 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL13892906 | 0.76 | BCL9 (0.64) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |