SCHEMBL4435225

SCHEMBL4435225

CC(C)(C)OOC(=O)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
ALDH1A1 P00352 7/20 0.50
LMNA P02545 1/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 2/20 0.46
PKM P14618 1/20 0.46
TSHR P16473 1/20 0.45
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10996751 0.86 MAPT (0.53) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL521069 0.80 MAPT (0.57) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL388383 0.80 MAPT (0.51) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL9710536 0.80 ALDH1A1 (0.57) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL491370 0.78 ALDH1A1 (0.55) ALDH1A1LMNAKMT2ASMN1; SMN2TDP1
SCHEMBL9878038 0.78 ALDH1A1 (0.50) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL11794354 0.78 ALDH1A1 (0.49) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL31154474 0.78 LMNA (0.52) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL9710538 0.78 MAPT (0.55) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL398701 0.78 LMNA (0.73) MAPTALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
EP-4667512-A1 INCREASED AREA STRETCH RATIO FOR CAPACITOR FILMS MADE OF A BIAXIALLY ORIENTED POLYPROPYLENE FILM Borealis GmbH (AT) 2025-12-24 EP disclosed
CN-118834330-A Method for preparing modified propylene-based polymer and modified propylene-based polymer prepared by method SK新技术株式会社 2024-10-25 CN disclosed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
EP-3898237-B1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES BOREALIS AG (AT) 2024-04-17 EP disclosed
CN-117203269-A Biaxially oriented polypropylene film after heat treatment 博里利斯股份公司 2023-12-08 CN disclosed
CN-116323174-A Multilayer sheet comprising a foamed layer suitable for food packaging 北欧化工公司 2023-06-23 CN disclosed
CN-115885009-A HMS PP foaming board with good compressive strength and recovery rate 北欧化工公司 2023-03-31 CN disclosed
EP-4086299-A1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM Borealis AG (AT) 2022-11-09 EP disclosed
EP-3898237-A1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES Borealis AG (AT) 2021-10-27 EP disclosed
EP-1391482-B1 Polypropylene composition BOREALIS TECH OY (FI) 2009-05-20 EP disclosed
EP-1294782-B1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS POLYOLEFINE GMBH (AT) 2007-01-10 EP disclosed
US-6797778-B2 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AU) 2004-09-28 US disclosed
EP-1391482-A1 Polypropylene composition Borealis GmbH (AT) 2004-02-25 EP disclosed
EP-1382638-A1 Polypropylene composition with improved stiffness and toughness Borealis GmbH (AT) 2004-01-21 EP disclosed
US-20030176590-A1 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AT) 2003-09-18 US disclosed
EP-1294782-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE Borealis GmbH (AT) 2003-03-26 EP disclosed
EP-1211284-A1 Semi-finished products or moulded materials of improved toughness made from propylene polymers Borealis GmbH (AT) 2002-06-05 EP disclosed
EP-1167404-A1 Polyolefin products with improved toughness, strength and heat resistance Borealis GmbH (AT) 2002-01-02 EP disclosed
WO-2001098385-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS GMBH (AT) 2001-12-27 WO disclosed