Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879803 | 0.85 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9879088 | 0.83 | GAA (0.75) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL9879098 | 0.82 | MEN1 (0.65) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9879486 | 0.79 | KMT2A (1.00) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9878625 | 0.79 | POLB (0.53) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9878974 | 0.77 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9879392 | 0.77 | KMT2A (0.74) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9878755 | 0.72 | SLC2A1 (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9878693 | 0.71 | SLC2A1 (0.45) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9878282 | 0.71 | NPC1 (0.48) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |