Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879486 | 0.85 | KMT2A (1.00) | KMT2AMEN1PDE9AGAAMAPT | |
| SCHEMBL9879390 | 0.79 | MEN1 (0.61) | KMT2AMEN1PABPC1PDE9AGAA | |
| SCHEMBL9879088 | 0.78 | GAA (0.75) | KMT2AMEN1GAANAMPTMAPT | |
| SCHEMBL9878068 | 0.77 | MEN1 (0.65) | KMT2AMEN1GAANAMPTMAPT | |
| SCHEMBL9879098 | 0.77 | MEN1 (0.65) | KMT2AMEN1PDE9AGAANAMPT | |
| SCHEMBL9879379 | 0.76 | MEN1 (0.64) | KMT2AMEN1PABPC1PDE9AGAA | |
| SCHEMBL9879803 | 0.73 | MEN1 (0.60) | KMT2AMEN1GAANAMPTMAPT | |
| SCHEMBL9879014 | 0.73 | KMT2A (0.60) | KMT2AMEN1PABPC1PDE9AGAA | |
| SCHEMBL9879015 | 0.73 | KMT2A (0.60) | KMT2AMEN1PABPC1PDE9AGAA | |
| SCHEMBL15201247 | 0.72 | KMT2A (0.68) | KMT2AMEN1GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |