Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879392 | 0.85 | KMT2A (0.74) | KMT2AMEN1TAAR1NCOA1NCOA3 | |
| SCHEMBL15201247 | 0.81 | KMT2A (0.68) | KMT2AMEN1TAAR1NCOA1NCOA3 | |
| SCHEMBL9879088 | 0.80 | GAA (0.75) | KMT2AMEN1GAAHTTMAPT | |
| SCHEMBL4471232 | 0.80 | KMT2A (0.67) | KMT2AMEN1TAAR1NCOA1NCOA3 | |
| SCHEMBL9879098 | 0.79 | MEN1 (0.65) | KMT2AMEN1RECQLGAAHTT | |
| SCHEMBL9878068 | 0.79 | MEN1 (0.65) | KMT2AMEN1GAANPC1MAPT | |
| SCHEMBL9879379 | 0.78 | MEN1 (0.64) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL15201279 | 0.76 | ALDH1A1 (0.62) | KMT2AMEN1TAAR1NCOA1NCOA3 | |
| SCHEMBL31436032 | 0.76 | NPC1 (0.67) | KMT2AMEN1TAAR1NCOA1NCOA3 | |
| SCHEMBL9879390 | 0.76 | MEN1 (0.61) | KMT2AMEN1GAANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |