Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324689 | 0.91 | RAB9A (0.41) | KDM4EHSP90AB1MAPTSMN1; SMN2PIM1 | |
| SCHEMBL9878242 | 0.85 | PIM1 (0.39) | KDM4EMAPTSMN1; SMN2PIM1MEN1 | |
| SCHEMBL12231276 | 0.82 | HSP90AB1 (0.52) | KDM4EHSP90AB1MAPTMEN1KMT2A | |
| SCHEMBL31069850 | 0.77 | ALDH1A1 (0.48) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31069851 | 0.77 | ALDH1A1 (0.48) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL481238 | 0.77 | ALDH1A1 (0.48) | KDM4EMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7324849 | 0.75 | MAPT (0.57) | HSP90AB1MAPTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL28836032 | 0.74 | KDM4E (0.41) | KDM4EMAPTSMN1; SMN2PIM1MEN1 | |
| SCHEMBL6331318 | 0.71 | MAPT (0.49) | KDM4EMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL9816215 | 0.68 | PRKCI (0.46) | KDM4EHSP90AB1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |