Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657483 | 0.84 | SMN1; SMN2 (0.59) | AXLNPSR1RAB9ASMN1; SMN2PDE3B | |
| SCHEMBL5565984 | 0.79 | AXL (0.58) | AXLNPSR1RAB9ASMN1; SMN2PDE3B | |
| SCHEMBL11438109 | 0.79 | AXL (0.58) | AXLRAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL10549335 | 0.73 | AXL (0.51) | AXLRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2375581 | 0.73 | AXL (1.00) | AXLRAB9ASMN1; SMN2PDE3BPDE3A | |
| SCHEMBL45369 | 0.71 | ALDH1A1 (0.64) | NPSR1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11637547 | 0.71 | SMN1; SMN2 (0.51) | AXLSMN1; SMN2PDE3BPDE3AMAPT | |
| SCHEMBL11846026 | 0.70 | AXL (0.92) | AXLRAB9ASMN1; SMN2PDE3BPDE3A | |
| SCHEMBL9879241 | 0.70 | MEN1 (0.50) | AXLPDE3BPDE3ACA1CA2 | |
| SCHEMBL6858216 | 0.70 | AXL (0.51) | AXLNPSR1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069271-A | Preparation [1] chromene is the method for [4,3-c] pyrazole compound also | BOOTS CO PLC (GB) | 1993-02-24 | — | — | CN | disclosed |
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |
| CN-1053921-A | Therapeutical agent | BOOTS CO PLC (GB) | 1991-08-21 | — | — | CN | disclosed |