Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761152 | 0.92 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL836840 | 0.92 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Bicarbonate SCHEMBL22204362 | 0.88 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL30916812 | 0.86 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL30916819 | 0.86 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL30916817 | 0.86 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL867302 | 0.86 | THRB (0.68) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL2325699 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| Phosphoric Acid SCHEMBL3464242 | 0.83 | TSHR (0.62) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15636 | 0.82 | THRB (0.74) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730757-B1 | ELECTROLYTE FOR PHOTOVOLTAIC DEVICE AS WELL AS PHOTOVOLTAIC DEVICE AND DYE-SENSITIZED SOLAR CELL INCLUDING THAT ELECTROLYTE | YOKOHAMA RUBBER CO LTD (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-8481849-B2 | Layered clay mineral that may be organically modified layered and an ionic liquid such as a quaternary ammonium salt, imidazolium salt, pyridinium salt or pyrrolidinium salt; performance equal to, or better than, a counter electrode using a platinum thin film | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-7875209-B2 | Photovoltaic device comprising conductive polyaniline | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| US-7497975-B2 | Organic polymer and a conductive polyaniline in an organic solvent | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-20080217586-A1 | Organic polymer and a conductive polyaniline in an organic solvent | THE YOKOHAMA RUBBER CO., LTD (JP) | 2008-09-11 | — | — | US | disclosed |
| US-20080142074-A1 | METHOD FOR PRODUCING CONDUCTIVE POLYANILINE | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2008-06-19 | — | — | US | disclosed |
| US-7351359-B2 | Oxidative polymerization of aniline or its derivative in the presence of a sulfonic acid or water-insoluble organic polymer having a protonic acid group in an aqueous layer and a water-insoluble organic solvent layer; also present are oxidizing agent, molecular weight adjuster and a phase transfer agent | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20050218381-A1 | Oxidative polymerization of aniline or its derivative in the presence of a sulfonic acid or water-insoluble organic polymer having a protonic acid group in an aqueous layer and a water-insoluble organic solvent layer; also present are oxidizing agent, molecular weight adjuster and a phase transfer agent | THE YOKOHAMA RUBBER CO., LTD. | 2005-10-06 | — | — | US | disclosed |