Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879128 | 0.81 | MEN1 (0.49) | ALDH1A1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL9879215 | 0.78 | MEN1 (0.37) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL10382652 | 0.77 | MAPT (0.55) | ALDH1A1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL8625894 | 0.69 | MAOB (0.42) | ALDH1A1TDP1KMT2ATHRBL3MBTL1 | |
| SCHEMBL12297731 | 0.69 | GAA (0.44) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL109980 | 0.68 | TRPA1 (0.62) | ALDH1A1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL31521298 | 0.68 | TRPA1 (0.62) | ALDH1A1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL29763174 | 0.68 | TRPA1 (0.62) | ALDH1A1MAPTTDP1MEN1CYP3A4 | |
| SCHEMBL8619935 | 0.67 | CD274 (0.54) | ALDH1A1MAPTTDP1KMT2ATHRB | |
| SCHEMBL11704123 | 0.66 | RAB9A (0.44) | MEN1KMT2APDE4AATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |