Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879215 | 0.85 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9878737 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL9536843 | 0.79 | MAPT (0.48) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL9879241 | 0.73 | MEN1 (0.50) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL11022631 | 0.69 | TP53 (0.67) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL12775753 | 0.69 | ALDH1A1 (0.71) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL8621001 | 0.67 | KMT2A (0.58) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL12989008 | 0.67 | PDCD1 (0.50) | MEN1KMT2AALOX15HSD17B10PDCD1 | |
| SCHEMBL7786291 | 0.66 | MEN1 (1.00) | MEN1KMT2AEGFRPIM1MAPT | |
| SCHEMBL11797236 | 0.66 | EGFR (0.84) | MEN1KMT2AEGFRPIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |