SCHEMBL987879

SCHEMBL987879

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2I)n1

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.45
GAA P10253 1/20 0.41
CDK1 P06493 1/20 0.37
FBP1 P09467 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TP53 P04637 1/20 0.36
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489600 1.00 ALDH1A1 (0.46) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL29360781 1.00 ALDH1A1 (0.46) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL2893387 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL2892755 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
Potassium SCHEMBL2892705 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL2892703 0.99 ALDH1A1 (0.48) ALDH1A1KDM4ENPC1MAPTGAA
Lithium SCHEMBL2893392 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL2892748 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
Ammonia Solution, Strong SCHEMBL2895237 0.99 ALDH1A1 (0.45) ALDH1A1KDM4ENPC1MAPTGAA
SCHEMBL2895226 0.99 MAPT (0.46) ALDH1A1KDM4ENPC1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220275391-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2022-09-01 US claimed
EP-2931034-B2 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2022-04-27 EP claimed
EP-3284346-B1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2021-07-07 EP claimed
EP-3137456-B1 PYRIDAZINONE HERBICIDES FMC CORP (US) 2021-06-02 EP claimed
US-20200095602-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-03-26 US claimed
CN-106458926-B Pyridazinone herbicides FMC公司 2020-01-03 CN claimed
US-10118917-B2 Pyridazinone herbicides FMC CORPORATION 2018-11-06 US claimed
EP-2931034-B1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS BAYER CROPSCIENCE AG (DE) 2018-06-13 EP claimed
EP-2713733-B1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BRASSICA, SUCH AS B. NAPUS, PLANTS BAYER IP GMBH (DE) 2018-03-14 EP claimed
EP-3284346-A1 USE OF ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS Bayer Intellectual Property GmbH (DE) 2018-02-21 EP claimed
EP-2052616-A1 Herbicide safener combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052614-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052605-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052603-A1 Application of 2-lodo-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl] benzol sulphonamide and/or its salts for inhibiting unwanted plant growth in selected agricultural crop cultures or non-cultivated land Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052610-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052612-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052606-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052615-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052609-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-2052611-A1 Herbicide combination Bayer CropScience AG (DE) 2009-04-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095602-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS LCT, HTT, GLO1 ALDH1A1 2379/4885KDM4E 3529/4885NPC1 4443/4885
US-20220275391-A1 METHODS OF USING ALS INHIBITOR HERBICIDES FOR CONTROL OF UNWANTED VEGETATION IN ALS INHIBITOR HERBICIDE TOLERANT BETA VULGARIS PLANTS LCT, HTT, GLO1 ALDH1A1 2379/4885KDM4E 3529/4885NPC1 4443/4885
US-10118917-B2 Pyridazinone herbicides CBR3, NOX5, NR5A2 ALDH1A1 1685/4885KDM4E 1868/4885NPC1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.