Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265637 | 0.83 | GSTP1 (0.51) | SLC2A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL9266330 | 0.79 | TYMP (0.50) | SLC2A1TYMPPTGS2MEN1KMT2A | |
| SCHEMBL9262778 | 0.78 | TYMP (0.51) | SLC2A1TYMPPTGS2MEN1KMT2A | |
| SCHEMBL9259612 | 0.78 | KEAP1 (0.47) | KEAP1NFE2L2TYMPPTGS2MEN1 | |
| SCHEMBL9268241 | 0.77 | SLC2A1 (0.63) | SLC2A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL9455077 | 0.76 | KEAP1 (0.49) | KEAP1NFE2L2TYMPPTGS2MEN1 | |
| SCHEMBL9270359 | 0.75 | SLC2A1 (0.78) | SLC2A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL4469241 | 0.74 | SLC2A1 (0.51) | SLC2A1SCN9ACHEK2 | |
| SCHEMBL9266167 | 0.74 | SLC2A1 (0.51) | SLC2A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL9269889 | 0.74 | PDGFRA (0.49) | CYP1A2POLBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |