Stavudine Triphosphate

Stavudine Triphosphate

SCHEMBL987898

Cc1cn([C@H]2C=C[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
ALB P02768 1/20 0.60
ADRA1A P35348 1/20 0.60
BLM P54132 1/20 0.60
POLA1 P09884 1/20 0.59
POLD1 P28340 1/20 0.59
BCHE P06276 10/20 0.51
TK1 P04183 3/20 0.48
P2RY2 P41231 1/20 0.48
P2RY6 Q15077 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stavudine Triphosphate SCHEMBL26731736 1.00 POLB (0.60) POLBALDH1A1LMNAALBADRA1A
SCHEMBL26309128 0.98 POLB (0.62) POLBALDH1A1LMNAALBADRA1A
SCHEMBL26731712 0.98 POLB (0.62) POLBALDH1A1LMNAALBADRA1A
SCHEMBL26731814 0.89 ALDH1A1 (0.67) POLBALDH1A1LMNAALBADRA1A
SCHEMBL124991 0.89 ALDH1A1 (0.67) POLBALDH1A1LMNAALBADRA1A
SCHEMBL26309146 0.85 POLB (0.56) POLBALDH1A1LMNAALBADRA1A
SCHEMBL9856521 0.81 POLG (0.50) POLBPOLA1POLD1P2RY2P2RY6
SCHEMBL26309162 0.81 POLB (0.53) POLBALDH1A1LMNAALBADRA1A
SCHEMBL18855348 0.80 POLB (0.68) POLBPOLA1POLD1BCHETK1
SCHEMBL3031874 0.80 POLB (0.68) POLBPOLA1POLD1BCHETK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024238925-A2 COMPOSITIONS AND METHODS FOR INDUCING VIRAL MIMICRY IN CANCER CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-11-21 WO claimed
EP-0517986-B1 Transformed erythrocytes, process for preparing the same, and their use in pharmaceutical compositions EUROP COMMUNITIES (LU) 1997-09-10 EP claimed
US-5576177-A DETERMINING EFFICACY OF HUMAN T-CELL LEUKEMIA/LYMPHOMA INFECTION TREATMENT ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 1996-11-19 US claimed
CN-120051271-A Methods for treating infectious diseases 欣扬生医股份有限公司 2025-05-27 CN disclosed
EP-4522128-A1 METHOD FOR TREATING INFECTIOUS DISEASE Suntec Medical, Inc. (US) 2025-03-19 EP disclosed
US-20250073163-A1 METHOD FOR TREATING INFECTIOUS DISEASE SUNTEC MEDICAL INC (US) 2025-03-06 US disclosed
WO-2024238925-A2 COMPOSITIONS AND METHODS FOR INDUCING VIRAL MIMICRY IN CANCER CELLS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-11-21 WO disclosed
WO-2023220086-A1 METHOD FOR TREATING INFECTIOUS DISEASE SUNTEC MEDICAL, INC. (US) 2023-11-16 WO disclosed
WO-2023178127-A1 METHODS OF TREATING MEDICAL CONDITIONS USING STAMPIDINE OR A RELATED COMPOUND ROME THERAPEUTICS, INC. (US) 2023-09-21 WO disclosed
US-7875422-B2 in an enveloped virus-infected mammalian individual by testing on an enzyme packed into an enveloped virus, such as HIV, recovered from a biological sample, such as blood or plasma CAVIDI AB (SE) 2011-01-25 US disclosed
US-20100021888-A1 Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes BOARD OF REGENTS 2010-01-28 US disclosed
US-7393634-B1 Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2008-07-01 US disclosed
EP-1395676-B1 VIRAL DRUG SUSCEPTIBILITY TESTING CAVIDI TECH AB (SE) 2006-01-18 EP disclosed
US-20040170958-A1 Viral drug susceptibility testing EUROPEAN INVESTMENT BANK (LU) 2004-09-02 US disclosed
WO-2001027330-A2 SCREENING FOR DISEASE SUSCEPTIBILITY BY GENOTYPING THE CCR5 AND CCR2 GENES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2001-04-19 WO disclosed
WO-2001012831-A2 ANTI-BACTERIAL AND ANTI-VIRAL COMPOSITIONS AND METHODS UT-BATTELLE, LLC (US) 2001-02-22 WO disclosed
US-5753221-A CONTAINING TRIPHOSPHORYLATED NUCLEOSIDE ANALOG WHICH INHIBITS REVERSE TRANSCRIPTASE; VIRICIDES COMMUNAUTE ECONOMIQUE EUROPEENE (LU) 1998-05-19 US disclosed
EP-0517986-B1 Transformed erythrocytes, process for preparing the same, and their use in pharmaceutical compositions EUROP COMMUNITIES (LU) 1997-09-10 EP disclosed
EP-0517986-A1 Transformed erythrocytes, process for preparing the same, and their use in pharmaceutical compositions COMMUNAUTE ECONOMIQUE EUROPEENNE (CEE) (LU) 1992-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250073163-A1 METHOD FOR TREATING INFECTIOUS DISEASE CD14, PML, SARS1 POLB 369/4885ALDH1A1 4505/4885LMNA 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.