Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | SAT1 | P21673 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14505542 | 0.86 | CYP2C19 (0.56) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL27822246 | 0.78 | CA5A (0.33) | CA1CA2 | |
| SCHEMBL9615777 | 0.77 | CYP2C19 (0.39) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL6660667 | 0.77 | CYP2C19 (0.43) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL21053421 | 0.76 | CA2 (0.55) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL6493 | 0.76 | — | — | |
| SCHEMBL177824 | 0.75 | — | — | |
| SCHEMBL12473093 | 0.75 | CYP2C19 (0.38) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL15872014 | 0.75 | CA1 (0.56) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| Hydrochloric Acid SCHEMBL11225061 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123506-A1 | Acid-group-substituted diphenylazetidinones process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH | 2007-05-31 | — | — | US | disclosed |
| US-20070123506-A1 | Acid-group-substituted diphenylazetidinones process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH | 2007-05-31 | — | — | US | disclosed |
| US-7176193-B2 | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176193-B2 | Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-02-13 | — | — | US | disclosed |
| US-5057276-A | Dissolving ionomeric polymer and reagent in solvent, adding water, and removing solvent | MILES INC. (US) | 1991-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123506-A1 | Acid-group-substituted diphenylazetidinones process for their preparation, medicaments comprising these compounds, and their use | CYP2D6, QDPR, CYP2A6 | CYP2C19 11/4885CYP1A2 23/4885MEN1 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.