Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164756 | 0.91 | CA2 (0.43) | CA2RAPGEF4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17774691 | 0.91 | POLB (0.41) | CA2RAPGEF4ALDH1A1MAPTKDM4E | |
| SCHEMBL17774690 | 0.91 | CA2 (0.39) | CYP19A1CA2RAPGEF4ALDH1A1SMN1; SMN2 | |
| SCHEMBL9878790 | 0.89 | CA2 (0.41) | CA2RAPGEF4ALDH1A1MAPTKDM4E | |
| SCHEMBL10389511 | 0.87 | CYP2D6 (0.42) | CYP19A1CA2RAPGEF4ALDH1A1MAPT | |
| SCHEMBL17774677 | 0.87 | CA2 (0.40) | CYP19A1CA2RAPGEF4ALDH1A1SMN1; SMN2 | |
| SCHEMBL17774706 | 0.86 | RECQL (0.45) | CA2RAPGEF4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10899520 | 0.86 | SMN1; SMN2 (0.37) | CYP19A1CA2RAPGEF4ALDH1A1SMN1; SMN2 | |
| SCHEMBL10576785 | 0.85 | RAPGEF4 (0.55) | CYP19A1RAPGEF4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10630292 | 0.84 | KMT2A (0.41) | CA2RAPGEF4ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872822-B2 | Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition | L'OREAL (FR) | 2018-01-23 | — | — | US | disclosed |
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | L'OREAL (FR) | 2016-05-26 | — | — | US | disclosed |
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0245603-B1 | AROMATIC AMINOSULFONE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| US-4851527-A | Water-soluble triphendioxazine compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| US-4785098-A | BLUE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0245603-A2 | Aromatic aminosulfone compounds and process for their preparation | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| US-4577015-A | Triphendioxazine vinyl sulphone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| EP-0153599-A2 | Triphenedioxazine vinylsulfonyl dyestuffs | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143826-A1 | PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION | KRT18, ARSA, SQOR | CYP19A1 824/4885CA2 86/4885RAPGEF4 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.