Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190361 | 0.78 | — | — | |
| SCHEMBL215399 | 0.76 | XDH (0.50) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL10412824 | 0.76 | TNKS (0.37) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL1553874 | 0.75 | ALDH1A1 (0.42) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL9752458 | 0.74 | FFAR4 (0.44) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL12802084 | 0.73 | FFAR4 (0.46) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL7167695 | 0.73 | XDH (0.40) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL10873667 | 0.71 | XDH (0.39) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL1158732 | 0.71 | XDH (0.39) | ALDH1A1PPARGPPARDPPARACYP3A4 | |
| SCHEMBL10659903 | 0.71 | FFAR4 (0.41) | ALDH1A1PPARGPPARDPPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003070-A | Antilipemic agents; arteriosclerosis; antibiotics | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | claimed |
| EP-0350445-A1 | Substituted azacyclohexyl derivatives | CIBA-GEIGY AG (CH) | 1990-01-10 | — | — | EP | claimed |
| JP-2056487-A | — | — | None | — | — | JP | disclosed |
| US-5003070-A | Antilipemic agents; arteriosclerosis; antibiotics | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-5003070-A | Antilipemic agents; arteriosclerosis; antibiotics | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4954580-A | ADHESIVES, SEALING, COATING, ENCAPSULATION | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| JP-H0256487-A | SUBSTITUTED AZACYCLOHEXYL DERIVATIVE | CIBA GEIGY AG | 1990-02-26 | — | — | JP | disclosed |
| EP-0350445-A1 | Substituted azacyclohexyl derivatives | CIBA-GEIGY AG (CH) | 1990-01-10 | — | — | EP | disclosed |
| EP-0350445-A1 | Substituted azacyclohexyl derivatives | CIBA-GEIGY AG (CH) | 1990-01-10 | — | — | EP | disclosed |
| EP-0319472-A2 | Epoxy siloxanes | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |