SCHEMBL1553874

SCHEMBL1553874

C=CCc1cc(C)cc(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 1/20 0.42
CYP3A4 P08684 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 2/20 0.41
XDH P47989 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPT P10636 2/20 0.40
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH2 P05091 1/20 0.40
AKR1B1 P15121 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420726 0.84 ALDH1A1 (0.48) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL16950585 0.84 TACR1 (0.37) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL8125707 0.84 ALDH1A1 (0.36) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL12559946 0.81 ALDH1A1 (0.55) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL215399 0.80 XDH (0.50) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL22701030 0.78 ALDH1A1 (0.39) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL12802084 0.77 FFAR4 (0.46) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL2137377 0.77 TAAR1 (0.50) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL5568614 0.77 PGK1 (0.33) PGK1PGK2
SCHEMBL31481296 0.77 TAAR1 (0.50) ALDH1A1PPARGPPARDPPARACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106847691-A A kind of rectification diode cleaning method 安徽兆利光电科技有限公司 2017-06-13 CN claimed
CN-109265588-B Fluorine-containing polymer and method for producing same 北京航天爱锐科技有限责任公司 2020-12-18 CN disclosed
CN-109265588-A Fluoropolymer and preparation method thereof 北京航天爱锐科技有限责任公司 2019-01-25 CN disclosed
CN-106847691-A A kind of rectification diode cleaning method 安徽兆利光电科技有限公司 2017-06-13 CN disclosed
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
US-9309188-B2 Method for allylating and vinylating aryl, heteroaryl, alkyl, and alkene halogenides using transition metal catalysis Saitigo GmbH (DE) 2016-04-12 US disclosed
CN-102731722-B For the production of the method for modified conjugated diene polymer, modified conjugated diene polymer and polymer composition SUMITOMO CHEMICAL CO., LTD. (JP) 2016-03-16 CN disclosed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
CN-102573458-B Monoalkyl sulfosuccinates in pesticide formulations and applications as hydrotropes AKZO NOBEL CHEMICALS INT BV 2015-05-27 CN disclosed
EP-0410379-B1 Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins MERRELL DOW PHARMA (US) 1996-01-31 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
US-5068465-A Hypotensive agents or enzyme inhibitors for treatment of hypertension MERRELL DOW PHARMACEUTICALS INC. (US) 1991-11-26 US disclosed
EP-0410379-A2 Pharmaceutically active 3-aryl and 3-heteroaryl-2-fluoro-1-olefins MERRELL DOW PHARMACEUTICALS INC. (US) 1991-01-30 EP disclosed
US-4981868-A ENZYME INHIBITORS, HYPOTENSIVES MERRELL DOW PHARMACEUTICAL (US) 1991-01-01 US disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed