Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.41 |
| ▸ | DRD3 | P35462 | 12/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878579 | 0.80 | DRD2 (0.41) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL8635112 | 0.69 | DRD2 (0.40) | DRD2DRD3HTR2B | |
| SCHEMBL14059506 | 0.67 | GAA (0.56) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL4524534 | 0.64 | IMPDH2 (0.41) | DRD2DRD3LTB4RLTB4R2LTA4H | |
| SCHEMBL13825739 | 0.62 | DRD2 (0.53) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL8231800 | 0.62 | DRD2 (0.53) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL8229208 | 0.62 | DRD2 (0.53) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL8232785 | 0.62 | DRD2 (0.53) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL8228508 | 0.62 | DRD2 (0.53) | DRD2DRD3HTR2BLTB4RLTB4R2 | |
| SCHEMBL4445356 | 0.62 | MAPT (0.37) | DRD2DRD3HTR2BLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012255-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-22 | — | — | WO | disclosed |