Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521098 | 0.91 | KDM4E (0.34) | KDM4EMAPT | |
| SCHEMBL9879351 | 0.76 | HRH2 (0.31) | KDM4EMAPT | |
| SCHEMBL9521933 | 0.72 | MAPK1 (0.50) | KDM4EMAPT | |
| SCHEMBL29209494 | 0.68 | GAA (0.51) | MAPT | |
| SCHEMBL20304522 | 0.67 | KMT2A (0.43) | KDM4EMAPT | |
| SCHEMBL2036963 | 0.66 | MLYCD (0.35) | MAPT | |
| SCHEMBL14740772 | 0.65 | HCAR2 (0.44) | KDM4E | |
| SCHEMBL1200949 | 0.64 | NPC1 (0.59) | KDM4EMAPT | |
| SCHEMBL9521084 | 0.64 | KDM4E (0.32) | KDM4E | |
| SCHEMBL26315587 | 0.64 | KMT2A (0.43) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1989008651-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |