Anthraquinone

Anthraquinone

SCHEMBL9879416

O=C(Cl)c1ccc(C(=O)Cl)cc1.O=C1c2ccccc2C(=O)c2ccccc21

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
CDC25B P30305 2/20 0.57
TTR P02766 2/20 0.55
PTPRC P08575 3/20 0.48
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
APAF1 O14727 2/20 0.48
TDP2 O95551 2/20 0.48
IDO1 P14902 1/20 0.48
DNMT1 P26358 1/20 0.48
DNMT3L Q9UJW3 1/20 0.48
DNMT3A Q9Y6K1 1/20 0.48
MAPT P10636 4/20 0.48
HTT P42858 3/20 0.48
S100A4 P26447 2/20 0.48
LMNA P02545 2/20 0.48
NPC1 O15118 2/20 0.48
MAPK1 P28482 2/20 0.48
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL698020 0.87 TTR (0.69) KMT2AMEN1CDC25BTTRPTPRC
SCHEMBL7551130 0.86 PTPRC (0.65) KMT2AMEN1CDC25BTTRPTPRC
SCHEMBL3300661 0.86 TTR (0.67) KMT2AMEN1TTRPTPRCBCL2
Anthraquinone SCHEMBL7092793 0.85 MEN1 (0.71) KMT2AMEN1CDC25BTTRPTPRC
Anthraquinone SCHEMBL11041458 0.82 MEN1 (0.67) KMT2AMEN1CDC25BTTRPTPRC
SCHEMBL30876050 0.81 ALDH1A1 (0.43) KMT2AMEN1MAPTLMNANPC1
SCHEMBL28399814 0.79 TTR (0.59) KMT2AMEN1CDC25BTTRPTPRC
SCHEMBL28397117 0.79 TTR (0.59) KMT2AMEN1CDC25BTTRPTPRC
Benzene SCHEMBL10386399 0.79 ALDH1A1 (0.54) MAPTMAPK1CES2POLBCES1
SCHEMBL20587670 0.79 ALDH1A1 (0.59) MAPTHTTLMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990589-A Engineering thermoplastic resin RAYCHEM LIMITED (GB) 1991-02-05 US disclosed