SCHEMBL9879448

SCHEMBL9879448

FC(F)(F)COc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
THRB P10828 1/20 0.41
G6PD P11413 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
S1PR1 P21453 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
SSTR4 P31391 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28060228 0.86 RXRA (0.50) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL28288419 0.81 MAPT (0.52) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL19768706 0.81 HSD17B10 (0.49) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL26655537 0.77 SSTR4 (0.40) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL22024912 0.77 SSTR4 (0.40) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL8089358 0.75 RXRA (0.49) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL30087620 0.74 RXRA (0.44) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL29635641 0.74 L3MBTL1 (0.48) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL10499330 0.74 L3MBTL1 (0.48) KMT2AMEN1MAPTL3MBTL1KDM4E
SCHEMBL9879447 0.73 IDO1 (0.32) L3MBTL1RXRARXRBRXRGIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047584-A Process for the preparation of pentahaloethoxy benzoyl halide compounds OCCIDENTAL CHEMICAL CORP. (US) 1991-09-10 US disclosed