SCHEMBL9879447

SCHEMBL9879447

FCC(F)(F)Oc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.32
CYP19A1 P11511 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10917461 0.74 TSHR (0.36)
SCHEMBL8439300 0.74
SCHEMBL4523641 0.74 TSHR (0.38) RXRARXRBRXRG
SCHEMBL1400220 0.74 HTR7 (0.38) IDO1L3MBTL1
SCHEMBL9231619 0.74 ALDH1A1 (0.44) L3MBTL1
SCHEMBL9879448 0.73 KMT2A (0.41) IDO1L3MBTL1RXRARXRBRXRG
SCHEMBL943073 0.73 DDB1 (0.33)
SCHEMBL5176422 0.72 TSHR (0.38) IDO1L3MBTL1
SCHEMBL16835442 0.72 ELANE (0.36)
SCHEMBL11399983 0.70 ALDH1A1 (0.53) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047584-A Process for the preparation of pentahaloethoxy benzoyl halide compounds OCCIDENTAL CHEMICAL CORP. (US) 1991-09-10 US disclosed