Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024344 | 0.83 | POLB (1.00) | POLBPKMALDH1A1KMT2AHPGD | |
| SCHEMBL18003531 | 0.82 | SMN1; SMN2 (0.51) | POLBALDH1A1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL18003534 | 0.81 | POLB (0.70) | POLBKMT2AHPGDSMN1; SMN2TSHR | |
| SCHEMBL8265140 | 0.79 | BACE1 (0.67) | POLBALDH1A1HPGDTSHRSCN9A | |
| SCHEMBL9878113 | 0.78 | PKM (1.00) | POLBPKMALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27787220 | 0.76 | POLB (0.64) | POLBPKMALDH1A1KMT2AHPGD | |
| SCHEMBL18003930 | 0.76 | FABP4 (0.43) | POLBPKMALDH1A1KMT2AHPGD | |
| SCHEMBL25350548 | 0.73 | PKM (0.68) | POLBPKMALDH1A1KMT2AHPGD | |
| SCHEMBL9879803 | 0.73 | MEN1 (0.60) | POLBALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL26039905 | 0.72 | ALDH1A1 (0.70) | POLBALDH1A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |