Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TLR4 | O00206 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298766 | 0.83 | LMNA (0.64) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL30618855 | 0.83 | LMNA (0.64) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL9064363 | 0.77 | LMNA (0.67) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL5943455 | 0.77 | LMNA (0.67) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL2094087 | 0.76 | HTT (0.61) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL2094084 | 0.76 | HTT (0.61) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL8693298 | 0.75 | NFE2L2 (0.52) | LMNAKMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL95238 | 0.75 | LMNA (1.00) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL5407816 | 0.75 | LMNA (0.64) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL29361707 | 0.75 | LMNA (1.00) | LMNAGAAKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | claimed |
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | claimed |
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0003021-A1 | Cyano-oligomer compositions and processes thereof | GAF CORPORATION (US) | 1979-07-25 | — | — | EP | disclosed |
| US-4128536-A | ULTRAVIOLET LIGHT ABSORBERS | GAF CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |