Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524646 | 0.79 | TP53 (0.45) | TP53MEN1KMT2A | |
| SCHEMBL16168685 | 0.73 | MEN1 (0.53) | MEN1KMT2ADRD1 | |
| SCHEMBL7774816 | 0.73 | DRD1 (0.49) | MEN1KMT2ADRD1 | |
| SCHEMBL9524857 | 0.72 | RPS6KA5 (0.61) | DRD1 | |
| SCHEMBL7770192 | 0.71 | BRD4 (0.39) | — | |
| SCHEMBL7774503 | 0.71 | BRD4 (0.39) | — | |
| SCHEMBL10388437 | 0.70 | DRD1 (0.47) | MEN1KMT2ADRD1 | |
| SCHEMBL9525557 | 0.70 | MAPK1 (0.51) | MEN1KMT2ADRD1 | |
| SCHEMBL19041065 | 0.70 | LMNA (0.49) | MEN1KMT2ALMNA | |
| SCHEMBL10054042 | 0.70 | DRD1 (0.53) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |