Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077743 | 0.85 | ATM (0.45) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL202301 | 0.85 | ACE (0.48) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL202300 | 0.85 | ACE (0.48) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL1022969 | 0.85 | ACE (0.48) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL14237836 | 0.85 | ATM (0.45) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL16187224 | 0.85 | ATM (0.45) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL1021093 | 0.84 | ATM (0.44) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL3509553 | 0.84 | ATM (0.44) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL3509552 | 0.84 | ATM (0.44) | ATMHSD17B10USP2SMN1; SMN2CHRM2 | |
| SCHEMBL200923 | 0.83 | ATM (0.46) | ATMHSD17B10USP2SMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213326-B1 | 2,5-DIMETHYL PYRROLE DERIVATIVES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4837225-A | ENCEPHALOTROPIC AND PSYCHOTROPIC EFFECTS | CASSELL AKTIENGESELLSCHAFT (DE) | 1989-06-06 | — | — | US | disclosed |
| EP-0213326-A1 | 2,5-Dimethyl pyrrole derivatives, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1987-03-11 | — | — | EP | disclosed |