SCHEMBL1022969

SCHEMBL1022969

CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.48
ATM Q13315 1/20 0.47
HSD17B10 Q99714 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.38
USP2 O75604 1/20 0.38
PREP P48147 2/20 0.37
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202300 1.00 ACE (0.48) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL202301 1.00 ACE (0.48) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL16187224 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL14237836 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL26077743 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL1249539 0.87 HSD17B10 (0.46) ATMHSD17B10SMN1; SMN2USP2PREP
SCHEMBL3509553 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL9879848 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL3509552 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL1021093 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118634264-A Efficient composite traditional Chinese medicine antibacterial agent and preparation method and application thereof 博尔纳生物科技(江门)有限公司 2024-09-13 CN claimed
CN-116925193-A Method for synthesizing polypeptide for preventing or treating novel coronavirus 深圳翰宇药业股份有限公司 2023-10-24 CN claimed
CN-111057128-B Sulfur-containing isoindolone cyclic peptide derivative and preparation method thereof 哈尔滨师范大学 2023-05-16 CN claimed
US-20040030155-A1 Process for preparing active esters ONO PHARMACEUTICAL CO., LTD. (JP) 2004-02-12 US claimed
EP-1350790-A1 PROCESS FOR PREPARING ACTIVE ESTERS ONO PHARMACEUTICAL CO., LTD. (JP) 2003-10-08 EP claimed
US-12624122-B2 Affinity maturated TAG72 specific single chain antibodies H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2026-05-12 US disclosed
US-12612598-B2 Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy IOVANCE BIOTHERAPEUTICS, INC. (US) 2026-04-28 US disclosed
EP-4720088-A1 CONSTRAINED PEPTIDE INHIBITORS OF LRRK2-FADD INTERACTIONS University of Georgia Research Foundation, Inc. (US) 2026-04-08 EP disclosed
EP-4720089-A1 COMPOSITIONS AND METHODS FOR IMAGING AND TREATING ENDOMETRIOSIS Endomet Biosciences, Inc. (US) 2026-04-08 EP disclosed
EP-4713348-A1 DOUBLY CONSTRAINED PEPTIDES AS ALLOSTERIC INHIBITORS OF LEUCINE RICH REPEAT KINASE 2 University of Georgia Research Foundation, Inc. (US) 2026-03-25 EP disclosed
US-12565520-B2 Chemically-stabilized allosteric modulators of leucine-rich repeat kinase 2 (LRRK2) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2026-03-03 US disclosed
EP-4662235-A1 METHOD OF CHEMICAL SYNTHESIS OF SINGLE-CHAIN ANTIBODY FRAGMENTS AND PRODUCTS THEREBY OBTAINED Figini, Mariangela (IT) 2025-12-17 EP disclosed
EP-0574135-B1 Process for producing peptide derivatives and salts thereof JAPAN ENERGY CORP (JP) 1998-11-18 EP disclosed
WO-1998050029-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed
US-5644028-A Process for producing peptide derivatives and salts therefor JAPAN ENERGY CORPORATION (JP) 1997-07-01 US disclosed
EP-0574135-A1 Process for producing peptide derivatives and salts thereof JAPAN ENERGY CORPORATION (JP) 1993-12-15 EP disclosed
WO-1993001174-A1 THIAZOLIDINE DERIVATIVES AND THEIR USE AS ANTI-VIRAL COMPOUNDS GLAXO GROUP LIMITED (GB) 1993-01-21 WO disclosed
US-4904680-A IMMUNOLOGY SANKYO COMPANY, LIMITED (JP) 1990-02-27 US disclosed
EP-0173441-B1 AMINO ACID DERIVATIVES HAVING ANTI-TUMOR ACTIVITY AND COMPOSITIONS CONTAINING THEM SANKYO COMPANY LIMITED (JP) 1990-01-24 EP disclosed
EP-0173441-A1 Amino acid derivatives having anti-tumor activity and compositions containing them SANKYO COMPANY LIMITED (JP) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612598-B2 Enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy IL2, ICOS, IL2RA ACE 4748/4885ATM 163/4885HSD17B10 2793/4885
US-20040030155-A1 Process for preparing active esters CES1, CYP3A4, CYP3A5 ACE 289/4885ATM 4804/4885HSD17B10 123/4885
US-12624122-B2 Affinity maturated TAG72 specific single chain antibodies IGLV6-57, CD74, IGSF11 ACE 4528/4885ATM 2769/4885HSD17B10 3717/4885
US-12565520-B2 Chemically-stabilized allosteric modulators of leucine-rich repeat kinase 2 (LRRK2) LRRK2, SNCA, PARK7 ACE 4066/4885ATM 424/4885HSD17B10 4463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.