SCHEMBL202300

SCHEMBL202300

CC(C)(C)OC(=O)N1CSC[C@@H]1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.48
ATM Q13315 1/20 0.47
HSD17B10 Q99714 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.38
USP2 O75604 1/20 0.38
PREP P48147 2/20 0.37
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022969 1.00 ACE (0.48) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL202301 1.00 ACE (0.48) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL16187224 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL14237836 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL26077743 0.87 ATM (0.45) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL1249539 0.87 HSD17B10 (0.46) ATMHSD17B10SMN1; SMN2USP2PREP
SCHEMBL3509553 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL9879848 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL3509552 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2
SCHEMBL1021093 0.85 ATM (0.44) ACEATMHSD17B10SMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057128-B Sulfur-containing isoindolone cyclic peptide derivative and preparation method thereof 哈尔滨师范大学 2023-05-16 CN claimed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 ZHOU YUHANG (US) 2025-09-11 US disclosed
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES AUCKLAND UNISERVICES LTD (NZ) 2025-09-11 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4413985-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2024-08-14 EP disclosed
EP-4384533-A1 LIPIDATED POLYMYXIN ANALOGUES Auckland Uniservices Limited (NZ) 2024-06-19 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
CN-111057128-B Sulfur-containing isoindolone cyclic peptide derivative and preparation method thereof 哈尔滨师范大学 2023-05-16 CN disclosed
EP-1799639-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION Glenmark Pharmaceuticals S.A. (CH) 2007-06-27 EP disclosed
WO-2007069020-A2 N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-06-21 WO disclosed
US-7230002-B2 Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof GLENMARK PHARMACEUTICALS LTD. (IN) 2007-06-12 US disclosed
US-7205323-B2 Dipeptidyl peptidase IV inhibitors pharmaceutical compositions containing them, and process for their preparation GLENMARK PHARMACEUTICALS S.A. (CH) 2007-04-17 US disclosed
US-20060142585-A1 Novel dipeptidyl peptidase IV inhibitors pharmaceutical compositions containing them, and process for their preparation GLENMARK PHARMACETUCALS, S.A. 2006-06-29 US disclosed
WO-2006040625-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION GLENMARK PHARMACEUTICALS S.A. (US) 2006-04-20 WO disclosed
US-20050192324-A1 Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof GLENMARK PHARMACEUTICALS LTD. (IN) 2005-09-01 US disclosed
WO-2005075426-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF GLENMARK PHARMACEUTICALS LTD. (US) 2005-08-18 WO disclosed
WO-2005058849-A1 NEW DIPEPTIDYL PEPTIDASE IN INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LTD. (US) 2005-06-30 WO disclosed
CN-1592746-A LFA-1 antagonist compounds GENENTECH INC (US) 2005-03-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142585-A1 Novel dipeptidyl peptidase IV inhibitors pharmaceutical compositions containing them, and process for their preparation DPP4, DPP3, DPP7 ACE 12/4885ATM 4661/4885HSD17B10 789/4885
US-20250282827-A1 LIPIDATED POLYMYXIN ANALOGUES PHOSPHO1, PCTP, PTMS ACE 3181/4885ATM 4786/4885HSD17B10 3505/4885
US-20250281424-A1 SMALL MOLECULE ANTAGONISTS OF PF4 PF4, F12, F2 ACE 4608/4885ATM 2816/4885HSD17B10 1989/4885
US-20050192324-A1 Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof DPP4, DPP3, DPP7 ACE 10/4885ATM 4827/4885HSD17B10 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.