Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521548 | 0.69 | MEN1 (0.49) | MAPK1CYP19A1MAPTMEN1KMT2A | |
| SCHEMBL11205372 | 0.67 | TP53 (0.36) | MAPK1GAATP53CYP19A1MAPT | |
| Fluindione SCHEMBL309362 | 0.66 | MAPT (0.68) | MAPK1GAATP53CYP19A1MAPT | |
| Fluindione SCHEMBL29362659 | 0.66 | MAPT (0.68) | MAPK1GAATP53CYP19A1MAPT | |
| SCHEMBL13940537 | 0.66 | MEN1 (0.41) | MAPK1GAATP53MAPTMEN1 | |
| SCHEMBL22691592 | 0.65 | HTR7 (0.40) | GAAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4048521 | 0.63 | MEN1 (0.38) | MAPK1GAATP53MAPTMEN1 | |
| SCHEMBL68097 | 0.63 | PIM1 (0.39) | MAPK1GAATP53MAPTMEN1 | |
| SCHEMBL13302892 | 0.63 | ACHE (0.39) | MAPK1GAATP53MAPTMEN1 | |
| SCHEMBL68578 | 0.63 | ACHE (0.39) | MAPK1GAATP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452406-A1 | SUBSTITUTED SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| WO-1990007495-A1 | SUBSTITUTED SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-12 | — | — | WO | disclosed |