Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207304 | 0.88 | KMT2A (0.37) | TP53MAPK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11413848 | 0.73 | — | — | |
| SCHEMBL11200277 | 0.73 | MEN1 (0.33) | GAAALDH1A1MAPTMEN1SLC2A1 | |
| SCHEMBL11211362 | 0.72 | ALDH1A1 (0.44) | TP53SLC6A3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11201233 | 0.71 | ELANE (0.39) | MAPK1GAACYP19A1SLC6A3ALDH1A1 | |
| SCHEMBL9879925 | 0.67 | MAPK1 (0.40) | TP53MAPK1GAACYP19A1ALDH1A1 | |
| SCHEMBL11404541 | 0.66 | EPHX1 (0.40) | TP53MAPK1GAAALDH1A1MAPT | |
| SCHEMBL11402204 | 0.66 | KMT2A (0.34) | TP53MAPK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13940537 | 0.64 | MEN1 (0.41) | TP53MAPK1GAAALDH1A1MAPT | |
| SCHEMBL68097 | 0.61 | PIM1 (0.39) | TP53MAPK1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091041-A2 | Vinylogous carboxamides, process for preparing them and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-10-12 | — | — | EP | disclosed |