Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866202 | 0.97 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTNPC1RAB9ANR1H4 | |
| SCHEMBL9865073 | 0.96 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTNPC1RAB9ANR1H4 | |
| SCHEMBL9866706 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL2906610 | 0.76 | HDAC3 (0.46) | SMN1; SMN2HTTALDH1A1MAPTLTA4H | |
| SCHEMBL9879968 | 0.75 | HTT (0.60) | SMN1; SMN2HTTNPC1RAB9ANR1H4 | |
| SCHEMBL7147082 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTNPC1RAB9ANR1H4 | |
| SCHEMBL12487487 | 0.74 | CCR6 (0.36) | HTTALDH1A1KMT2ALTA4HHDAC2 | |
| SCHEMBL9866193 | 0.74 | HTT (0.58) | SMN1; SMN2HTTNPC1RAB9ANR1H4 | |
| SCHEMBL7095566 | 0.74 | HDAC2 (0.45) | KMT2AMEN1POLBLTA4HHDAC2 | |
| SCHEMBL28745974 | 0.74 | GAA (0.79) | SMN1; SMN2HTTNPC1RAB9ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |