Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866193 | 0.97 | HTT (0.58) | HTTSMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL9865066 | 0.96 | HTT (0.57) | HTTSMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL9865134 | 0.87 | HTT (0.53) | HTTSMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL9335791 | 0.84 | HTT (0.49) | HTTRAB9AKMT2AMEN1MAPT | |
| SCHEMBL9867129 | 0.84 | HDAC6 (0.49) | HTTRAB9AKMT2AMEN1 | |
| SCHEMBL10444691 | 0.84 | HDAC6 (0.49) | HTTRAB9AKMT2AMEN1 | |
| SCHEMBL14264247 | 0.83 | HTT (0.64) | HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6400257 | 0.83 | MGLL (0.72) | RAB9AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9866050 | 0.81 | GAA (0.54) | HTTSMN1; SMN2RAB9AKMT2AALDH1A1 | |
| SCHEMBL5306095 | 0.78 | NR4A2 (0.63) | HTTSMN1; SMN2KMT2ANR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |