SCHEMBL9880602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723691	0.81	PARP1 (0.54)	PARP1KMT2AMEN1NPSR1ALDH1A1
	SCHEMBL10017800	0.78	EPHX1 (0.42)	CYP2C19NPC1RAB9ASMN1; SMN2HTR2C
	SCHEMBL11469003	0.76	L3MBTL1 (0.38)	PARP1KMT2AMEN1P2RX4NPSR1
	SCHEMBL9880600	0.74	LMNA (0.56)	KMT2AMEN1P2RX4NPSR1P2RX1
	SCHEMBL19864297	0.72	ALDH1A1 (0.55)	KMT2AMEN1NPSR1ALDH1A1CYP1A2
	SCHEMBL4077619	0.72	CNR1 (0.53)	KMT2AMEN1NPSR1ALDH1A1ADORA3
	SCHEMBL23443667	0.72	PARP1 (0.42)	PARP1KMT2AMEN1P2RX4NPSR1
	SCHEMBL9880614	0.72	PARP1 (0.64)	PARP1KMT2AMEN1NPSR1ALDH1A1
	SCHEMBL6346314	0.71	ALDH1A1 (0.56)	KMT2AMEN1P2RX4NPSR1P2RX1
	SCHEMBL9880608	0.71	ALDH1A1 (0.45)	PARP1KMT2AMEN1P2RX4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.