Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 5/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCB | P05771 | 4/20 | 0.62 |
| ▸ | PRKCA | P17252 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | PRKACA | P17612 | 4/20 | 0.60 |
| ▸ | PRKACG | P22612 | 3/20 | 0.60 |
| ▸ | PRKACB | P22694 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985509 | 0.87 | PRKCG (0.68) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL117035 | 0.87 | PRKCG (0.62) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| Hydrochloric Acid SCHEMBL117220 | 0.86 | LMNA (0.63) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7431698 | 0.85 | PRKACA (0.67) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7436845 | 0.85 | PRKCG (0.63) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9543751 | 0.84 | PRKCG (0.64) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7424197 | 0.83 | PRKACA (0.64) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL117620 | 0.83 | KCNA5 (0.59) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7435898 | 0.81 | PRKCG (0.65) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL7429623 | 0.81 | PRKD3 (0.56) | PRKCGPRKCZPRKCDPRKD3PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135984-A1 | DUAL-ACTION INHBITORS AND METHODS OF USING SAME | AERIE PHARMACEUTICALS, INC. | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135984-A1 | DUAL-ACTION INHBITORS AND METHODS OF USING SAME | SLC6A2, ROCK2, SLC6A4 | PRKCG 1031/4885PRKCZ 1405/4885PRKCD 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.