Sarmentine

Sarmentine

SCHEMBL988356

CCCCCC=CC=CC(=O)N1CCCC1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
FASN P49327 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
CNR1 P21554 2/20 0.46
CNR2 P34972 2/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sarmentine SCHEMBL988355 1.00 KDM4E (0.48) KDM4EFASNL3MBTL1CNR1CNR2
(2E,4Z-Decadienoyl)Pyrrolidine SCHEMBL988489 1.00 KDM4E (0.48) KDM4EFASNL3MBTL1CNR1CNR2
SCHEMBL17091586 0.98 FASN (0.50) KDM4EFASNCNR1CNR2
(2E,4Z-Decadienoyl)Piperidine SCHEMBL989746 0.98 L3MBTL1 (0.47) KDM4EFASNL3MBTL1CNR1CNR2
(2E,4Z-Decadienoyl)Hexamethleneimine SCHEMBL990447 0.98 L3MBTL1 (0.47) KDM4EFASNL3MBTL1CNR1CNR2
(2E,4Z-Decadienoyl)Piperidine SCHEMBL4881424 0.98 L3MBTL1 (0.47) KDM4EFASNL3MBTL1CNR1CNR2
SCHEMBL17091584 0.98 FASN (0.50) KDM4EFASNCNR1CNR2
(2E,4Z-Decadienoyl)Piperidine SCHEMBL989745 0.98 L3MBTL1 (0.47) KDM4EFASNL3MBTL1CNR1CNR2
SCHEMBL30649149 0.98 FASN (0.50) KDM4EFASNCNR1CNR2
SCHEMBL17091590 0.97 KDM4E (0.49) KDM4EFASNL3MBTL1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2710892-B1 Use of sarmentine and its analogs for controlling weeds MARRONE BIO INNOVATIONS INC (US) 2016-12-14 EP claimed
US-9179675-B2 Use of sarmentine and its analogs for controlling plant pests MARRONE BIO INNOVATIONS, INC. (US) 2015-11-10 US claimed
US-20150111749-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS PRO FARM GROUP, INC. 2015-04-23 US claimed
EP-2710892-A2 Use of sarmentine and its analogs for controlling plant pests Marrone Bio Innovations, Inc. (US) 2014-03-26 EP claimed
EP-2456305-A2 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS Marrone Bio Innovations, Inc. (US) 2012-05-30 EP claimed
WO-2011011415-A2 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS MARRONE BIO INNOVATIONS, INC. (US) 2011-01-27 WO claimed
US-20110021358-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS MARRONE BIO INNOVATIONS, INC. (US) 2011-01-27 US claimed
EP-2967044-B1 HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2018-01-03 EP disclosed
US-9832996-B2 Use of sarmentine and its analogues with an herbicide, and compositions thereof MARRONE BIO INNOVATIONS, INC. (US) 2017-12-05 US disclosed
US-20170196222-A9 Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof PRO FARM GROUP, INC. 2017-07-13 US disclosed
EP-2710892-B1 Use of sarmentine and its analogs for controlling weeds MARRONE BIO INNOVATIONS INC (US) 2016-12-14 EP disclosed
US-20160212999-A1 Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof MARRONE BIO INNOVATIONS INC (US) 2016-07-28 US disclosed
EP-2967044-A1 HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF Syngenta Participations AG (CH) 2016-01-20 EP disclosed
US-20130281294-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS PRO FARM GROUP, INC. 2013-10-24 US disclosed
US-8466192-B2 Use of sarmentine and its analogs for controlling plant pests MARRONE BIO INNOVATIONS, INC. (US) 2013-06-18 US disclosed
EP-2456305-A2 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS Marrone Bio Innovations, Inc. (US) 2012-05-30 EP disclosed
WO-2011112067-A1 A HERBAL COMPOSITION HAVING ANTI-OBESITY PROPERTY UNIVERSITI SAINS MALAYSIA (MY) 2011-09-15 WO disclosed
WO-2011011415-A2 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS MARRONE BIO INNOVATIONS, INC. (US) 2011-01-27 WO disclosed
US-20110021358-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS MARRONE BIO INNOVATIONS, INC. (US) 2011-01-27 US disclosed
US-20080038386-A1 Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition MOZA ASHOK K 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281294-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM KDM4E 436/4885FASN 1232/4885L3MBTL1 229/4885
US-20160212999-A1 Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof DDT, SRM, SMOX KDM4E 453/4885FASN 763/4885L3MBTL1 1807/4885
US-20170196222-A9 Use of Sarmentine and Its Analogues With an Herbicide, and Compositions Thereof DDT, SRM, SMOX KDM4E 453/4885FASN 763/4885L3MBTL1 1807/4885
US-20110021358-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM KDM4E 436/4885FASN 1232/4885L3MBTL1 229/4885
US-20150111749-A1 USE OF SARMENTINE AND ITS ANALOGS FOR CONTROLLING PLANT PESTS SARM1, SMOX, STOM KDM4E 436/4885FASN 1232/4885L3MBTL1 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.