Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 7/20 | 0.32 |
| ▸ | HTR2C | P28335 | 7/20 | 0.32 |
| ▸ | HTR2B | P41595 | 7/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168017 | 0.94 | HTR2A (0.36) | KMT2AALDH1A1CDK5CDK5R1GAA | |
| SCHEMBL14411028 | 0.92 | RAB9A (0.35) | KMT2AALDH1A1CDK5CDK5R1GAA | |
| SCHEMBL13168007 | 0.90 | HTR2A (0.37) | KMT2AALDH1A1GAAPOLBHTR2A | |
| SCHEMBL14411037 | 0.88 | KMT2A (0.35) | KMT2AALDH1A1GAAPOLBHTR2A | |
| SCHEMBL3400724 | 0.86 | HTR2A (0.39) | KMT2AALDH1A1GAAPOLBHTR2A | |
| SCHEMBL19463667 | 0.84 | ALDH1A1 (0.34) | KMT2AALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL13255364 | 0.81 | HTR2A (0.43) | KMT2AALDH1A1POLBHTR2AHTR2C | |
| SCHEMBL15579628 | 0.81 | ALDH1A1 (0.34) | KMT2AALDH1A1CDK5CDK5R1GAA | |
| SCHEMBL12658238 | 0.80 | HTR2C (0.38) | KMT2AALDH1A1CDK5CDK5R1GAA | |
| SCHEMBL13527244 | 0.79 | CDK5 (0.33) | KMT2AALDH1A1CDK5CDK5R1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673818-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8673818-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8334300-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSHAFT (DE) | 2012-12-18 | — | — | US | disclosed |
| US-8334300-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSHAFT (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-8193120-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2012-06-05 | — | — | US | disclosed |
| US-8193120-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110143943-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-06-16 | — | — | US | disclosed |
| US-20110143943-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-06-16 | — | — | US | disclosed |
| US-7915282-B2 | Preparation by intramolecular cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 2011-03-29 | — | — | US | disclosed |
| US-7915282-B2 | Preparation by intramolecular cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 2011-03-29 | — | — | US | disclosed |
| EP-1280770-B1 | C 2? PHENYL-SUBSTITUTED CYCLIC KETO-ENOLS USED AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2010-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143943-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, PDHX, AKR1C2 | KMT2A 844/4885ALDH1A1 2150/4885CDK5 474/4885 |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, PDHX, AKR1C2 | KMT2A 844/4885ALDH1A1 2150/4885CDK5 474/4885 |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, AKR1C4, AKR1C2 | KMT2A 890/4885ALDH1A1 1620/4885CDK5 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.