Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168007 | 0.96 | HTR2A (0.37) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL9883902 | 0.94 | KMT2A (0.35) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL14411028 | 0.88 | RAB9A (0.35) | KMT2APOLBALDH1A1TSHRCDK5 | |
| SCHEMBL13255364 | 0.86 | HTR2A (0.43) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL14411037 | 0.85 | KMT2A (0.35) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL3400724 | 0.83 | HTR2A (0.39) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL13527244 | 0.81 | CDK5 (0.33) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL13168023 | 0.81 | GABRA1 (0.33) | KMT2APOLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL10309275 | 0.79 | LIPG (0.38) | HTR2AHTR2CHTR2BKMT2APOLB | |
| SCHEMBL19463667 | 0.79 | ALDH1A1 (0.34) | HTR2AHTR2CHTR2BKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| EP-2218330-A1 | Process for the preparation of 2-ethyl-4,6-dimethylphenyl acetic acid by reacting 2-ethyl-4,6-dimethylbromobenzene with tert.-butylacetate | Bayer CropScience AG (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | DDT, DDC, DAO | HTR2A 3457/4885HTR2C 3381/4885HTR2B 2088/4885 |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | DDT, DDC, DAO | HTR2A 3457/4885HTR2C 3381/4885HTR2B 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.