Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209314 | 0.91 | ALOX15 (0.48) | GRM5ALOX15TDP1NOS3NOS1 | |
| SCHEMBL9611211 | 0.91 | GRM5 (0.56) | GRM5ALOX15TDP1ALDH1A1 | |
| SCHEMBL2640689 | 0.89 | GRM5 (0.53) | GRM5ALOX15TDP1ALDH1A1 | |
| SCHEMBL72823 | 0.85 | GRM5 (0.66) | GRM5ALOX15TDP1ALDH1A1 | |
| SCHEMBL14252062 | 0.82 | GRM5 (0.65) | GRM5FFAR1ALOX15TDP1ALDH1A1 | |
| SCHEMBL4577919 | 0.82 | GRM5 (0.49) | GRM5ALOX15TDP1ALDH1A1CA1 | |
| SCHEMBL14252340 | 0.82 | PGR (0.51) | ALOX15TDP1NOS3NOS1NOS2 | |
| SCHEMBL27186006 | 0.82 | GRM5 (0.49) | GRM5ALOX15TDP1ALDH1A1PGR | |
| SCHEMBL12314488 | 0.81 | ALOX15 (0.46) | GRM5ALOX15TDP1ALDH1A1CA1 | |
| SCHEMBL9885475 | 0.81 | GRM5 (0.56) | GRM5ALOX15TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586569-B1 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |