⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424618 | 0.79 | CES2 (0.43) | — | |
| SCHEMBL1045937 | 0.79 | TAAR1 (0.62) | — | |
| SCHEMBL5350956 | 0.78 | HSPA5 (0.38) | — | |
| SCHEMBL138361 | 0.78 | — | — | |
| SCHEMBL29943841 | 0.78 | — | — | |
| SCHEMBL1980626 | 0.78 | — | — | |
| SCHEMBL8526001 | 0.77 | TAAR1 (0.75) | — | |
| SCHEMBL3301625 | 0.77 | TAAR1 (0.59) | — | |
| Ammonia Solution, Strong SCHEMBL329693 | 0.76 | TAAR1 (0.52) | — | |
| SCHEMBL10365620 | 0.75 | TAAR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-20 | — | — | US | claimed |
| CN-115894486-B | Hydrogenated pyridoquinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| EP-4313943-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-02-07 | — | — | EP | claimed |
| CN-117043140-A | Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances | 拜耳公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115925675-A | Psamaplin A derivative and preparation method and application thereof | 中国海洋大学 | 2023-04-07 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-115894455-A | Quinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894486-A | Hydrogenated pyridoquinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-20220378816-A1 | 2-BENZYLIDENE HYDRAZINOADENOSINE COMPOUNDS HAVING A2A ADENOSINE RECEPTOR AGONISTIC ACTIVITY | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2022-12-01 | — | — | US | claimed |
| CN-112679400-B | Psamaplin A derivative and preparation method and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| WO-1998043969-A1 | INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | claimed |
| WO-1998002438-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-01-22 | — | — | WO | claimed |
| WO-1998002437-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-01-22 | — | — | WO | claimed |
| WO-1998002434-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1998-01-22 | — | — | WO | claimed |
| EP-0533781-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS. | PFIZER (US) | 1993-03-31 | — | — | EP | claimed |
| WO-1991019702-A1 | 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVES AND ANALOGS AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1991-12-26 | — | — | WO | claimed |
| US-4956366-A | GASTROINTESTINAL DISORDERS, ANTISECRETORY AGENTS FOR GASTRIC ACID SECRETION | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | claimed |
| EP-0299389-A2 | Substituted thieno-imidazole derivatives, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors, gastric protecting agents and as medicaments against intestinal inflammation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | claimed |
| EP-0048548-B1 | PHARMACEUTICAL COMPOSITIONS OF FUNGICIDAL TRIAZOLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0048548-A1 | Pharmaceutical compositions of fungicidal triazole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | claimed |