⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640304 | 0.79 | TAAR1 (0.39) | — | |
| SCHEMBL7394350 | 0.79 | TAAR1 (0.62) | — | |
| SCHEMBL29538515 | 0.79 | TAAR1 (0.62) | — | |
| SCHEMBL647527 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL98874 | 0.78 | — | — | |
| SCHEMBL3301625 | 0.77 | TAAR1 (0.59) | — | |
| SCHEMBL8526001 | 0.77 | TAAR1 (0.75) | — | |
| SCHEMBL14546326 | 0.75 | ACHE (0.37) | — | |
| SCHEMBL1585044 | 0.74 | — | — | |
| SCHEMBL283466 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569727-A | Preparation method of key intermediate of vitamin Li Xigu | 合肥菁科生物科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-111269205-B | Preparation method of C-aryl glycoside compound | 华侨大学 | 2023-05-26 | — | — | CN | claimed |
| CN-119569727-A | Preparation method of key intermediate of vitamin Li Xigu | 合肥菁科生物科技有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |
| CN-116891468-A | Thiazole compound and application thereof | 南京再明医药有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-114644631-A | KRAS G12C protein mutation inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-06-21 | — | — | CN | disclosed |
| WO-2022056447-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |
| US-11192856-B2 | Process for preparing alpha-carboxamide pyrrolidine derivatives | BIOGEN INC. (US) | 2021-12-07 | — | — | US | disclosed |
| EP-3845531-A1 | SUBSTITUTED PYRAZOLE FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Applied Pharmaceutical Science, Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |
| US-20200270206-A1 | PROCESS FOR PREPARING ALPHA-CARBOXAMIDE PYRROLIDINE DERIVATIVES | BIOGEN INC. | 2020-08-27 | — | — | US | disclosed |
| CN-111269205-A | Preparation method of C-aryl glycoside compound | 华侨大学 | 2020-06-12 | — | — | CN | disclosed |
| US-6534613-B2 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | EASTMAN CHEMICAL COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-6531602-B2 | Desilylation of a 2-pyridylsilane to form an alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020165397-A1 | 2-Pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL CO., LTD. | 2002-11-07 | — | — | US | disclosed |
| CN-1332753-A | Process for producing polyethylene | EASTMAN CHEM CO (US) | 2002-01-23 | — | — | CN | disclosed |
| US-20020007024-A1 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | WESTLAKE LONGVIEW CORPORATION | 2002-01-17 | — | — | US | disclosed |
| EP-1159314-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1035125-A2 | 2-Pyridylsilane, processes for producing and using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |
| WO-2000052067-A1 | PROCESS FOR PRODUCING POLYETHYLENE | EASTMAN CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| US-4282388-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |