SCHEMBL9889121

SCHEMBL9889121

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(-c3cc(-c4ccccc4)nc(-c4ccccc4)n3)cn2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.44
KMT2A Q03164 8/20 0.44
HPGD P15428 7/20 0.44
MAPT P10636 7/20 0.44
ALDH1A1 P00352 6/20 0.44
NTSR1 P30989 1/20 0.44
KDM4E B2RXH2 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CYP2C19 P33261 1/20 0.40
LMNA P02545 2/20 0.40
GLA P06280 1/20 0.40
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
ADORA2A P29274 2/20 0.39
ADORA1 P30542 2/20 0.39
MAPK1 P28482 2/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10246654 0.91 KDM4E (0.41) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL9889118 0.88 CYP19A1 (0.41) MEN1KMT2AMAPTALDH1A1NPSR1
SCHEMBL10246750 0.87 KDM4E (0.42) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL17952813 0.86 CHRNA7 (0.40) NPC1NFKB1RAB9ANFKB2RELA
SCHEMBL17483329 0.85 NPY5R (0.36) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL8400373 0.85 MEN1 (0.47) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL22126436 0.85 MEN1 (0.47) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL22126502 0.85 MEN1 (0.47) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL16171464 0.85 KMT2A (0.42) MEN1KMT2AHPGDMAPTALDH1A1
SCHEMBL22126467 0.84 KMT2A (0.44) MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-10651398-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-05-12 US disclosed
US-10276637-B2 Organic EL multi-color light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-30 US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170229660-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-9530969-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-9530969-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US disclosed
US-9130174-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-09-08 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L MEN1 1270/4885KMT2A 2152/4885HPGD 3432/4885
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 MEN1 260/4885KMT2A 2781/4885HPGD 4027/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L MEN1 1270/4885KMT2A 2152/4885HPGD 3432/4885
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L MEN1 1397/4885KMT2A 2201/4885HPGD 3171/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L MEN1 1397/4885KMT2A 2201/4885HPGD 3171/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 MEN1 260/4885KMT2A 2781/4885HPGD 4027/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L MEN1 1397/4885KMT2A 2201/4885HPGD 3171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.